| Date | Game | |
| Fri Sep 15 | at Kitty Harrison Invitational Chapel Hill, NC | |
| Fri Sep 15 | at Debbie Southern Fall Classic Greenville, SC | |
| Sat Sep 23 | at ITF 15K Hilton Head, S.C. | |
| Sat Sep 30 | at ITA All-American Championships Cary, N.C. | |
| Wed Oct 18 | at ITA Regional Championship Chapel Hill, N.C. | |
| Fri Oct 27 | at Roberta Alison Invite Tuscaloosa, AL | |
| Sat Jan 13 | vs Kansas Palm Springs, CA | |
| Fri Jan 19 | vs ETSU Clemson, SC | W 4-3 |
| Sun Jan 21 | vs Georgia State Clemson, SC | W 7-0 |
| Sun Jan 21 | vs Western Carolina Clemson, SC | W 7-0 |
Sat Jan 27
4:00 ET | vs Iowa Raleigh, SC | W 4-3 |
Sun Jan 28
4:00 ET | vs NC State Raleigh, SC | L 0-4 |
Sat Feb 3
12:00 ET | vs Charlotte Clemson, SC | W 4-2 |
Sat Feb 10
10:00 AM ET | vs Georgia Southern Clemson, SC | W 6-1 |
Sat Feb 10
3:00 ET | vs College of Charleston Clemson, SC | W 5-1 |
| Wed Feb 14 | at South Carolina Columbia, SC | L 1-6 |
Fri Feb 23
3:00 ET | at Syracuse * Syracuse, NY | L 3-4 |
Sun Feb 25
10:00 AM ET | at Boston College * Weymouth, MA | L 3-4 |
Fri Mar 1
5:00 ET | vs Virginia Tech * Clemson, SC | W 4-3 |
| Sun Mar 3 | vs Charleston Southern Clemson, SC | W 4-0 |
Sun Mar 3
12:00 ET | vs Virginia * Clemson, SC | L 0-4 |
Fri Mar 8
2:00 ET | at Duke * Durham, N.C. | L 0-4 |
Sat Mar 9
1:00 ET | at UNC * Chapel Hill, N.C. | L 0-4 |
| Fri Mar 15 | vs Radford Clemson, SC | W 6-1 |
| Fri Mar 22 | at Miami * Coral Gables, FL | |
Sun Mar 24
12:30 ET | at Florida State * Tallahassee, Fla. | L 0-4 |
Thu Mar 28
5:00 ET | vs Louisville * Clemson, SC | W 4-3 |
Sat Mar 30
12:00 ET | vs Notre Dame * Clemson, SC | L 1-4 |
| Fri Apr 5 | at Georgia Tech * Atlanta, GA | L 0-4 |
Fri Apr 5
12:00 ET | at Georgia Tech Atlanta, GA | |
Fri Apr 12
5:00 ET | vs Wake Forest * Clemson, S.C. | L 1-4 |
Sun Apr 14
12:00 ET | vs NC State * Clemson, SC | L 1-6 |
| Wed Apr 17 | vs ACC Championships Cary, NC | |
Wed Apr 17
12:30 ET | vs Boston College Cary, N.C. | W 4-3 |
Thu Apr 18
3:30 ET | vs Georgia Tech Cary, NC | W 4-3 |
Fri Apr 19
3:30 ET | vs NC State Cary, NC | L 0-4 |