| Date | Game | |
| Mon Nov 4, 7:00 ET | vs Maine Durham, NC | ACCN |
| Fri Nov 8, 6:00 ET | vs Army Durham, NC | ACCN |
| Tue Nov 12, 9:00 ET | vs Kentucky | ESPN |
| Sat Nov 16, 12:00 ET | vs Wofford Durham, NC | ACCN |
| Fri Nov 22, 10:30 ET | at Arizona Tuscon, AZ | ESPN2 |
| Tue Nov 26, 9:00 ET | vs Kansas Las Vegas, NV | ESPN |
| Fri Nov 29, 7:00 ET | vs Seattle Durham, NC | ACCN |
| Wed Dec 4, 9:15 ET | vs Auburn Durham, NC | ESPN |
| Sun Dec 8, 6:00 ET | at Louisville Louisville, Ky. | ACCN |
| Tue Dec 10, 7:00 ET | vs Incarnate Word Durham, NC | ACCN |
| Tue Dec 17, 7:00 ET | vs George Mason Durham, NC | ACCN |
| Sat Dec 21, 12:00 ET | at Georgia Tech Atlanta, GA | |
| Tue Dec 31, 4:30 ET | vs Virginia Tech Durham, NC | ACCN |
| Sat Jan 4, 2:15 ET | at SMU Dallas, Texas | The CW |
| Tue Jan 7, 7:00 ET | vs Pitt Durham, NC | ESPN |
| Sat Jan 11, 12:00 ET | vs Notre Dame Durham, NC | ESPN |
| Tue Jan 14, 9:00 ET | vs Miami Durham, NC | ESPN |
| Sat Jan 18 | at Boston College Chestnut Hill, Mass. | |
| Sat Jan 25, 4:30 ET | at Wake Forest Winston-Salem, NC | ESPN |
| Mon Jan 27, 8:30 ET | vs NC State Durham, NC | ESPN |
| Sat Feb 1, 6:30 ET | vs North Carolina Durham, N.C. | ESPN |
| Wed Feb 5, 7:00 ET | at Syracuse Syracuse, N.Y. | ESPN2 |
| Sat Feb 8, 6:00 ET | at Clemson Clemson, SC | ESPN |
| Wed Feb 12, 9:00 ET | vs California Durham, NC | ACCN |
| Sat Feb 15, 4:00 ET | vs Stanford Durham, NC | ABC |
| Mon Feb 17, 8:00 ET | at Virginia Charlottesville, VA | ESPN |
| Sat Feb 22, 8:00 ET | vs Illinois New York, NY | FOX |
| Tue Feb 25, 7:00 ET | at Miami Coral Gables, FL | ESPN |
| Sat Mar 1, 7:00 ET | vs Florida State Durham, NC | ACCN |
| Mon Mar 3, 7:00 ET | vs Wake Forest Durham, NC | ESPN |
| Sat Mar 8, 6:30 ET | at North Carolina Chapel Hill, NC | ESPN |