| Date | Game | |
| Mon Nov 4, 11:00 AM ET | vs Radford Durham, N.C. | W 89-36 |
| Thu Nov 7, 7:00 ET | at Liberty Lynchburg, Va. | W 83-67 |
| Sun Nov 10, 1:00 ET | at Maryland College Park, Md. | L 80-85 |
| Thu Nov 14, 7:00 ET | vs Dayton Durham, N.C. | W 84-49 |
| Sun Nov 17, 3:30 ET | at South Dakota State Brookings, S.D. | W 75-71 |
| Thu Nov 21, 7:00 ET | vs Belmont Durham, N.C. | W 79-47 |
| Mon Nov 25, 3:00 ET | vs Kansas State Henderson, Nev. | W 73-62 |
| Wed Nov 27, 4:30 ET | vs Oklahoma Henderson, Nev. | W 109-99 |
| Sun Dec 1, 12:00 ET | vs Columbia Durham, N.C. | W 77-61 |
| Thu Dec 5, 9:00 ET | at South Carolina | ESPN |
| Sun Dec 8, 4:00 ET | vs Virginia Tech | ACCN |
| Wed Dec 18, 7:00 ET | vs Wofford | ACCN |
| Sat Dec 21, 12:00 ET | at South Florida | ESPN2 |
| Thu Jan 2, 7:00 ET | at Boston College Chestnut Hill, Mass. | ACCNX |
| Sun Jan 5, 12:00 ET | vs Pittsburgh Durham, N.C. | ACCN |
| Thu Jan 9, 7:00 ET | at North Carolina Chapel Hill, N.C. | |
| Sun Jan 12, 7:00 ET | at Virginia Charlottesville, Va. | ACCN |
| Thu Jan 16, 8:00 ET | vs California Durham, NC | ACCN |
| Sun Jan 19, 1:00 ET | vs Stanford Durham, N.C. | ESPN2 |
| Thu Jan 23, 8:00 ET | at SMU Dallas, Texas | ACCN |
| Sun Jan 26, 2:00 ET | at Georgia Tech Atlanta, Ga. | ACCNX |
| Mon Feb 3, 7:00 ET | at NC State Raleigh, N.C. | ESPN2 |
| Thu Feb 6, 7:00 ET | vs Clemson Durham, N.C. | ACCNX |
| Sun Feb 9, 2:00 ET | vs Miami Durham, N.C. | ACCNX |
| Thu Feb 13, 6:00 ET | at Wake Forest Winston-Salem, N.C. | ACCNX |
| Mon Feb 17, 6:00 ET | at Notre Dame South Bend, Ind. | ESPN |
| Thu Feb 20, 7:00 ET | vs Louisville Durham, N.C. | ESPN2 |
| Sun Feb 23, 2:00 ET | vs Syracuse Durham, N.C. | The CW |
| Thu Feb 27, 7:00 ET | vs North Carolina Durham, N.C. | ESPN |
| Sun Mar 2, 6:00 ET | at Florida State Tallahassee, Fla. | ACCN |