| Date | Game | |
| Fri Feb 14, 8:00 ET | vs Texas Arlington, Texas | |
| Sat Feb 15, 4:00 ET | vs Oklahoma State Arlington, Texas | |
| Sun Feb 16, 11:30 AM ET | vs Arizona Arlington, Texas | |
| Wed Feb 19, 3:00 ET | vs Xavier Louisville, Ky. | |
| Fri Feb 21, 3:00 ET | vs Western Michigan Louisville, Ky. | |
| Sat Feb 22, 1:00 ET | vs Western Michigan Louisville, Ky. | |
| Sun Feb 23, 1:00 ET | vs Western Michigan Louisville, Ky. | |
| Wed Feb 26, 3:00 ET | vs Butler Louisville, Ky. | |
| Fri Feb 28, 3:00 ET | vs St. John's Louisville, Ky. | |
| Sat Mar 1, 1:00 ET | vs St. John's Louisville, Ky. | |
| Sun Mar 2, 1:00 ET | vs St. John's Louisville, Ky. | |
| Tue Mar 4, 3:00 ET | vs Morehead State Louisville, Ky. | |
| Fri Mar 7, 12:00 ET | vs UIC Louisville, Ky. | |
| Sat Mar 8, 1:00 ET | vs UIC Louisville, Ky. | |
| Sun Mar 9, 1:00 ET | vs UIC Louisville, Ky. | |
| Tue Mar 11, 3:00 ET | vs Lipscomb Louisville, Ky. | |
| Wed Mar 12, 3:00 ET | vs Oakland Louisville, Ky. | |
| Fri Mar 14, 6:00 ET | vs North Carolina Louisville, Ky. | |
| Sat Mar 15, 2:00 ET | vs North Carolina Louisville, Ky. | |
| Sun Mar 16, 1:00 ET | vs North Carolina Louisville, Ky. | |
| Tue Mar 18, 6:00 ET | vs Northern Kentucky Louisville, Ky. | |
| Fri Mar 21, 4:00 ET | at Virginia Tech Blacksburg, Va. | |
| Sat Mar 22, 3:00 ET | at Virginia Tech Blacksburg, Va. | |
| Sun Mar 23, 1:00 ET | at Virginia Tech Blacksburg, Va. | |
| Tue Mar 25, 6:00 ET | at Cincinnati Cincinnati, Ohio | |
| Fri Mar 28, 6:00 ET | vs Cal Louisville, Ky. | |
| Sat Mar 29, 2:00 ET | vs Cal Louisville, Ky. | |
| Sun Mar 30, 12:00 ET | vs Cal Louisville, Ky. | |
| Tue Apr 1, 6:00 ET | at Indiana Bloomington, Ind. | |
| Fri Apr 4, 6:00 ET | vs Boston College Louisville, Ky. | |
| Sat Apr 5, 2:00 ET | vs Boston College Louisville, Ky. | |
| Sun Apr 6, 1:00 ET | vs Boston College Louisville, Ky. | |
| Tue Apr 8, 6:00 ET | vs Kentucky Louisville, Ky. | |
| Fri Apr 11, 6:00 ET | at NC State Raleigh, N.C. | |
| Sat Apr 12, 3:00 ET | at NC State Raleigh, N.C. | |
| Sun Apr 13, 1:00 ET | at NC State Raleigh, N.C. | |
| Tue Apr 15, 6:00 ET | vs Western Kentucky Louisville, Ky. | |
| Thu Apr 17, 7:00 ET | at Clemson Clemson, S.C. | |
| Fri Apr 18, 7:00 ET | at Clemson Clemson, S.C. | |
| Sat Apr 19, 2:00 ET | at Clemson Clemson, S.C. | |
| Tue Apr 22, 6:30 ET | at Kentucky Lexington, Ky. | |
| Fri Apr 25, 6:00 ET | vs Florida State Louisville, Ky. | |
| Sat Apr 26, 2:00 ET | vs Florida State Louisville, Ky. | |
| Sun Apr 27, 1:00 ET | vs Florida State Louisville, Ky. | |
| Tue Apr 29, 6:00 ET | vs Eastern Kentucky Louisville, Ky. | |
| Thu May 1 | at Notre Dame South Bend, Ind. | |
| Fri May 2 | at Notre Dame South Bend, Ind. | |
| Sat May 3 | at Notre Dame South Bend, Ind. | |
| Tue May 6, 6:00 ET | vs Vanderbilt Louisville, Ky. | |
| Fri May 9, 6:00 ET | at Georgia Tech Atlanta, GA | |
| Sat May 10, 4:00 ET | at Georgia Tech Atlanta, GA | |
| Sun May 11, 1:00 ET | at Georgia Tech Atlanta, GA | |
| Tue May 13, 6:00 ET | vs Bellarmine Louisville, Ky. | |
| Thu May 15, 6:00 ET | vs Wake Forest Louisville, Ky. | |
| Fri May 16, 2:00 ET | vs Wake Forest Louisville, Ky. | |
| Sat May 17, 1:00 ET | vs Wake Forest Louisville, Ky. | |