| Date | Game | |
| Fri Feb 9, 10:00 AM ET | vs LIU Ft. Myers, Fla. | W 2-0 |
| Fri Feb 9, 2:30 ET | vs Georgetown University Ft. Myers, Fla. | W 4-1 |
| Sat Feb 10, 5:00 ET | vs Georgetown University Ft. Myers, Fla. | W 7-0 |
| Sat Feb 10, 7:30 ET | at Florida Gulf Coast Fort Myers, Fla. | W 6-0 |
| Sun Feb 11, 12:30 ET | at Florida Gulf Coast Fort Myers, Fla. | W 7-0 |
| Tue Feb 13, 5:00 ET | at FIU Miami, Fla. | W 11-2 |
| Thu Feb 15, 6:00 ET | at FAU Boca Raton, Fla. | W 2-1 |
| Fri Feb 16, 11:30 AM ET | vs Seton Hall Boca Raton, Fla. | W 12-4 |
| Fri Feb 16, 4:30 ET | at FAU Boca Raton, Fla. | L 3-6 |
| Sat Feb 17, 9:00 AM ET | vs Maine Boca Raton, Fla. | W 8-0 |
| Sat Feb 17, 11:15 AM ET | vs Michigan Boca Raton, Fla. | W 2-0 |
| Fri Feb 23, 1:00 ET | vs Furman Conway, S.C. | |
| Sat Feb 24, 10:00 AM ET | vs Furman Conway, S.C. | L 8-13 |
| Sat Feb 24, 3:30 ET | at Coastal Carolina Conway, S.C. | W 6-2 |
| Sun Feb 25, 9:30 AM ET | vs Bowling Green Conway, S.C. | W 11-3 |
| Tue Feb 27, 5:00 ET | vs Western Kentucky LOUISVILLE, Ky. | W 4-1 |
| Fri Mar 1, 10:30 AM ET | vs Villanova Tampa, Fla. | L 4-6 |
| Fri Mar 1, 3:30 ET | at USF Tampa, Fla. | L 1-3 |
| Sat Mar 2, 1:30 ET | vs Georgia Southern Tampa, Fla. | W 7-6 |
| Sat Mar 2, 4:00 ET | at USF Tampa, Fla. | L 3-4 |
| Sun Mar 3, 9:30 AM ET | vs Central Michigan Tampa, Fla. | W 7-2 |
| Wed Mar 6, 5:30 ET | vs Arizona LOUISVILLE, Ky. | W 5-3 |
| Sat Mar 9, 3:00 ET | vs Virginia Tech LOUISVILLE, Ky. | L 1-11 |
| Sat Mar 9, 5:00 ET | vs Virginia Tech LOUISVILLE, Ky. | L 2-5 |
| Sun Mar 10, 4:30 ET | vs Virginia Tech LOUISVILLE, Ky. | L 3-4 |
| Thu Mar 14, 7:00 ET | vs South Dakota LOUISVILLE, Ky. | W 8-5 |
| Fri Mar 15, 6:00 ET | vs Illinois LOUISVILLE, Ky. | L 0-6 |
| Sat Mar 16, 6:00 ET | vs Michigan LOUISVILLE, Ky. | W 12-4 |
| Sun Mar 17, 5:00 ET | vs Illinois LOUISVILLE, Ky. | W 5-4 |
| Tue Mar 19, 5:00 ET | at Miami Oxford, Ohio | |
| Tue Mar 19, 5:00 ET | at Miami Oxford, OH | L 7-8 |
| Fri Mar 22, 6:00 ET | vs Duke LOUISVILLE, Ky. | L 2-3 |
| Sat Mar 23, 1:00 ET | vs Duke LOUISVILLE, KY | W 2-1 |
| Sun Mar 24, 12:00 ET | vs Duke LOUISVILLE, KY | L 3-5 |
| Tue Mar 26, 6:00 ET | vs Indiana LOUISVILLE, KY | L 6-11 |
| Fri Mar 29, 3:00 ET | at Pittsburgh Pittsburgh, Pa. | W 3-2 |
| Fri Mar 29, 3:00 ET | at Pittsburgh Pittsburgh, Pa. | W 3-2 |
| Fri Mar 29, 6:00 ET | at Pittsburgh Pittsburgh, Pa. | L 4-9 |
| Sun Mar 31, 1:00 ET | at Pitt Pittsburgh, PA | W 9-0 |
| Tue Apr 2, 5:00 ET | at Northern Kentucky | |
| Fri Apr 5, 6:00 ET | vs Florida State Louisville, Ky. | W 5-4 |
| Sat Apr 6, 1:00 ET | vs Florida State Louisville, Ky. | L 4-8 |
| Sun Apr 7, 12:00 ET | vs Florida State Louisville, Ky. | L 3-4 |
| Fri Apr 12, 6:00 ET | at Georgia Tech Atlanta, Ga. | L 0-8 |
| Sat Apr 13, 2:00 ET | at Georgia Tech Atlanta, Ga. | W 4-1 |
| Sun Apr 14, 12:00 ET | at Georgia Tech Atlanta, Ga. | L 3-5 |
| Sun Apr 14, 12:00 ET | at Georgia Tech Atlanta, Ga. | |
| Tue Apr 16, 6:00 ET | at Eastern Kentucky Richmond, Ky. | L 2-6 |
| Fri Apr 19, 5:00 ET | at North Carolina Chapel Hill, N.C. | W 2-1 |
| Fri Apr 19, 5:00 ET | at North Carolina Chapel Hill, N.C. | W 2-1 |
| Sat Apr 20, 2:00 ET | at North Carolina Chapel Hill, N.C. | L 1-9 |
| Sat Apr 20, 4:30 ET | at North Carolina Chapel Hill, N.C. | L 6-7 |
| Fri Apr 26, 6:00 ET | vs Clemson LOUISVILLE, Ky. | L 5-6 |
| Sat Apr 27, 1:00 ET | vs Clemson LOUISVILLE, Ky. | W 6-3 |
| Sun Apr 28, 12:00 ET | vs Clemson LOUISVILLE, Ky. | L 5-11 |
| Tue Apr 30, 4:00 ET | vs Clemson Louisville, KY | |
| Fri May 3, 4:00 ET | at Boston College Chestnut Hill, Mass. | L 2-3 |
| Sat May 4, 1:00 ET | at Boston College Chestnut Hill, Mass. | L 3-4 |
| Sun May 5, 11:00 AM ET | at Boston College Chestnut Hill, Mass. | W 11-4 |
| Wed May 8 | vs ACC Championships Durham, N.C. | |
| Fri May 17 | vs NCAA Regionals | |
| Fri May 24 | vs NCAA Super Regionals | |
| Thu May 30 | vs Women's College World Series Oklahoma City, Okla. | |