| Date | Game | |
| Mon Nov 4, 5:00 ET | vs Mercyhurst South Bend, Ind. | W 105-61 |
| Sun Nov 10, 7:00 ET | at Purdue West Lafayette, Ind. | W 102-58 |
| Wed Nov 13, 7:00 ET | vs James Madison South Bend, Ind. | W 92-46 |
| Sun Nov 17, 2:00 ET | at Lafeyette Easton, PA | W 91-55 |
| Sat Nov 23, 4:00 ET | at USC Los Angeles, CA | W 74-61 |
| Fri Nov 29, 5:00 ET | vs TCU George Town, Cayman Islands | L 68-76 |
| Sat Nov 30, 5:00 ET | vs Utah George Town, Cayman Islands | L 67-78 |
| Thu Dec 5, 7:00 ET | vs Texas South Bend, Ind. | W 80-70 |
| Sun Dec 8, 12:00 ET | at Syracuse Syracuse, NY | W 93-62 |
| Thu Dec 12, 7:00 ET | vs UConn South Bend, Ind. | W 79-68 |
| Sun Dec 15, 2:00 ET | vs Eastern Michigan South Bend, Ind. | W 118-49 |
| Sun Dec 22, 2:00 ET | vs Loyola Maryland South Bend, Ind. | W 97-54 |
| Sun Dec 29, 12:00 ET | vs Virginia South Bend, Ind. | W 95-54 |
| Sun Jan 5, 1:00 ET | at North Carolina Chapel Hill, NC | W 76-66 |
| Thu Jan 9, 5:00 ET | vs Wake Forest South Bend, Ind. | W 100-64 |
| Sun Jan 12, 2:00 ET | at Clemson Clemson, SC | W 67-58 |
| Thu Jan 16, 6:00 ET | vs Georgia Tech South Bend, Ind. | W 81-66 |
| Sun Jan 19, 6:00 ET | vs SMU South Bend, Ind. | W 88-64 |
| Thu Jan 23, 7:00 ET | at Boston College Chestnut Hill, Mass. | W 89-63 |
| Thu Jan 30, 6:00 ET | at Virginia Tech Blacksburg, VA | W 77-61 |
| Sun Feb 2, 12:00 ET | at Louisville Louisville, Ky. | W 89-71 |
| Thu Feb 6, 8:30 ET | vs Stanford South Bend, Ind. | W 96-47 |
| Sun Feb 9, 2:00 ET | vs California South Bend, Ind. | W 91-52 |
| Thu Feb 13, 8:00 ET | at Pitt Pittsburgh, PA | W 88-57 |
| Mon Feb 17, 6:00 ET | vs Duke South Bend, Ind. | W 64-49 |
| Thu Feb 20, 7:00 ET | at Miami Coral Gables, FL | W 82-42 |
| Sun Feb 23, 12:00 ET | at NC State Raleigh, N.C. | L 95-104 |
| Thu Feb 27, 8:00 ET | vs Florida State South Bend, Ind. | L 81-86 |
| Sun Mar 2, 12:00 ET | vs Louisville South Bend, Ind. | W 72-59 |
| Fri Mar 7, 5:00 ET | vs California Greensboro, N.C. | W 73-64 |
| Sat Mar 8, 2:30 ET | vs Duke Greensboro, N.C. | L 56-61 |
| Fri Mar 21, 2:00 ET | vs Stephen F. Austin South Bend, Ind. | W 106-54 |
| Sun Mar 23, 1:00 ET | vs Michigan South Bend, Ind. | W 76-55 |
| Sat Mar 29, 1:00 ET | vs TCU Birmingham, Ala. | L 62-71 |