| Date | Game | |
| Sat Sep 5 | vs Miami Miami, OH | |
| Sat Sep 12 | at Marshall Huntington, W.V. | |
Sat Sep 12
4:00 ET | vs Austin Peay Pittsburgh, PA | W 55-0 |
| Sat Sep 19 | vs Richmond Pittsburgh, Pa. | |
Sat Sep 19
12:00 ET | vs Syracuse Pittsburgh, Pa. | W 21-10 |
| Sat Sep 26 | vs Duke Pittsburgh, Pa. | |
Sat Sep 26
12:00 ET | vs Louisville Pittsburgh, Pa. | W 23-20 |
| Sat Oct 3 | at Miami Coral Gables, FL | |
Sat Oct 3
12:00 ET | vs NC State Pittsburgh, Pa. | L 29-30 |
Sat Oct 10
4:00 ET | at Boston College Chestnut Hill, Mass. | L 30-31 |
| Sat Oct 17 | vs Notre Dame Pittsburgh, Pa. | |
Sat Oct 17
12:00 ET | at Miami Miami Gardens, Fla. | L 19-31 |
| Sat Oct 24 | vs Notre Dame Pittsburgh, Pa. | |
| Sat Oct 24 | vs Georgia Tech Pittsburgh, Pa. | |
Sat Oct 24
3:30 ET | vs Notre Dame Pittsburgh, Pa. | L 3-45 |
| Sat Oct 31 | at Florida State Tallahassee, Fla. | |
| Fri Nov 6 | vs Virginia Tech Pittsburgh, Pa. | |
Sat Nov 7
4:00 ET | at Florida State Tallahassee, Fla. | W 41-17 |
| Sat Nov 14 | at North Carolina Chapel Hill, N.C. | |
| Sat Nov 21 | at Virginia Charlottesville, Va. | |
Sat Nov 21
4:00 ET | vs Virginia Tech Pittsburgh, Pa. | W 47-14 |
| Sat Nov 28 | vs Syracuse Pittsburgh, Pa. | |
Sat Nov 28
3:30 ET | at Clemson Clemson, S.C. | L 17-52 |
Thu Dec 10
7:00 ET | at Georgia Tech Atlanta, Ga. | W 34-20 |