| Date | Game | |
| Thu Oct 28, 7:30 ET | vs Blue-Gold Dual Pittsburgh, Pa. | |
| Sun Nov 7 | vs Clarion Open Clarion, PA | |
| Fri Nov 12, 7:00 ET | at Buffalo Buffalo, NY | W 21-12 |
| Sat Nov 13, 7:00 ET | at Edinboro Edinboro, PA | W 28-20 |
| Sun Nov 21, 2:00 ET | at Lehigh Bethlehem, PA | L 9-26 |
| Mon Nov 22, 6:00 ET | vs Maryland Pittsburgh, PA | W 26-7 |
| Sun Dec 12, 1:00 ET | at Ohio State Columbus, OH | L 7-30 |
| Wed Dec 29 | vs Midlands Championships | |
| Sun Jan 9, 12:00 ET | vs Army Pittsburgh, PA | W 29-10 |
| Fri Jan 14, 7:00 ET | vs Arizona State Pittsburgh, PA | W 24-19 |
| Fri Jan 21, 7:00 ET | vs Virginia Pittsburgh, PA | W 25-10 |
| Sun Jan 30, 2:00 ET | vs Virginia Tech Pittsburgh, PA | L 12-24 |
| Fri Feb 4, 7:00 ET | at North Carolina Chapel Hill, N.C. | L 12-19 |
| Sun Feb 6, 2:00 ET | vs Columbia Pittsburgh, PA | W 30-5 |
| Fri Feb 11, 7:00 ET | vs NC State Pittsburgh, Pa. | L 9-26 |
| Fri Feb 18, 7:00 ET | at Duke Durham, N.C. | W 29-12 |
| Sun Mar 6 | vs 2022 ACC Wrestling Championship Charlottesville, VA | |
| Thu Mar 17 | vs 2022 NCAA Wrestling Championships Detroit, MI | |