| Date | Game | |
| Fri Feb 14, 4:00 ET | vs Bucknell Blacksburg, Va. | |
| Sat Feb 15, 3:00 ET | vs Bucknell Blacksburg, Va. | |
| Sun Feb 16, 1:00 ET | vs Bucknell Blacksburg, Va. | |
| Tue Feb 18, 4:00 ET | vs East Tennessee State Blacksburg, Va. | |
| Fri Feb 21, 4:00 ET | vs UNCG Blacksburg, Va. | |
| Sat Feb 22, 3:00 ET | vs UNCG Blacksburg, Va. | |
| Sun Feb 23, 1:00 ET | vs UNCG Blacksburg, Va. | |
| Tue Feb 25, 3:00 ET | at James Madison Harrisonburg, Va. | |
| Fri Feb 28, 12:00 ET | vs Indiana State Greenville, N.C. | |
| Sat Mar 1, 12:00 ET | vs Kent State Greenville, N.C. | |
| Sun Mar 2, 3:30 ET | at East Carolina Greenville, N.C. | |
| Tue Mar 4, 4:00 ET | vs Norfolk State Blacksburg, Va. | |
| Wed Mar 5, 3:00 ET | vs Norfolk State Blacksburg, Va. | |
| Fri Mar 7, 4:00 ET | vs Georgia Tech Blacksburg, Va. | |
| Sat Mar 8, 3:00 ET | at Georgia Tech Blacksburg, Va. | |
| Sun Mar 9, 1:00 ET | at Georgia Tech Blacksburg, Va. | |
| Tue Mar 11, 4:00 ET | vs James Madison Blacksburg, Va. | |
| Fri Mar 14, 6:00 ET | at NC State Raleigh, N.C. | |
| Sat Mar 15, 3:00 ET | at NC State Raleigh, N.C. | |
| Sun Mar 16, 1:00 ET | at NC State Raleigh, N.C. | |
| Tue Mar 18, 4:00 ET | vs VCU Blacksburg, Va. | |
| Fri Mar 21, 4:00 ET | vs Louisville Blacksburg, Va. | |
| Sat Mar 22, 3:00 ET | vs Louisville Blacksburg, Va. | |
| Sun Mar 23, 1:00 ET | vs Louisville Blacksburg, Va. | |
| Tue Mar 25, 6:00 ET | at Radford University Radford, Va. | |
| Fri Mar 28, 6:00 ET | at Wake Forest Winston-Salem, N.C. | |
| Sat Mar 29, 4:00 ET | at Wake Forest Winston-Salem, N.C. | |
| Sun Mar 30, 1:00 ET | at Wake Forest Winston-Salem, N.C. | |
| Tue Apr 1, 1:00 ET | vs Radford Blacksburg, Va. | |
| Fri Apr 4, 4:30 ET | at Notre Dame South Bend, Ind. | |
| Sat Apr 5, 2:00 ET | at Notre Dame South Bend, Ind. | |
| Sun Apr 6, 1:00 ET | at Notre Dame South Bend, Ind. | |
| Tue Apr 8, 6:00 ET | vs Troy Blacksburg, Va. | |
| Fri Apr 11, 6:00 ET | vs Florida State Blacksburg, Va. | |
| Sat Apr 12, 3:00 ET | vs Florida State Blacksburg, Va. | |
| Sun Apr 13, 12:00 ET | vs Florida State Blacksburg, Va. | |
| Tue Apr 15, 5:00 ET | at East Tennessee State Johnson City, Tenn. | |
| Fri Apr 18, 7:00 ET | vs North Carolina Blacksburg, Va. | |
| Sat Apr 19, 3:00 ET | vs North Carolina Blacksburg, Va. | |
| Sun Apr 20, 1:00 ET | vs North Carolina Blacksburg, Va. | |
| Tue Apr 22, 6:30 ET | at VCU Richmond, Va. | ESPN+ |
| Fri Apr 25, 6:00 ET | at Duke Durham, N.C. | |
| Sat Apr 26, 3:00 ET | at Duke Durham, N.C. | |
| Sun Apr 27, 1:00 ET | at Duke Durham, N.C. | |
| Tue Apr 29, 6:00 ET | vs Liberty Blacksburg, Va. | |
| Fri May 2, 6:00 ET | at Pitt Pittsburgh, Pa. | |
| Sat May 3, 3:00 ET | at Pitt Pittsburgh, Pa. | |
| Sun May 4, 1:00 ET | at Pitt Pittsburgh, Pa. | |
| Wed May 7, 6:00 ET | at Liberty Lynchburg, Va. | |
| Sat May 10, 3:00 ET | vs Mercer Blacksburg, Va. | |
| Sun May 11 | vs Mercer Lynchburg, Va. | |
| Sun May 11 | vs Mercer Lynchburg, Va. | |
| Sun May 11, 1:00 ET | vs Mercer Lynchburg, Va. | |
| Tue May 13, 6:00 ET | vs Marshall Blacksburg, Va. | |
| Thu May 15, 6:00 ET | vs Virginia Blacksburg, Va. | |
| Fri May 16, 3:00 ET | vs Virginia Blacksburg, Va. | |
| Sat May 17, 1:00 ET | vs Virginia Blacksburg, Va. | |