| Date | Game | |
| Wed Nov 25, 12:00 ET | vs Radford Cassell Coliseum, Blacksburg, VA | W 77-62 |
| Sat Nov 28, 8:00 ET | vs Temple | ESPNEWS |
| Sat Nov 28, 8:00 ET | vs Villanova Mohegan Sun, Uncasville, CT | W 81-73 |
| Sun Nov 29, 8:00 ET | vs South Florida Mohegan Sun, Uncasville, CT | W 77-59 |
| Thu Dec 3, 8:00 ET | vs VMI Cassell Coliseum, Blacksburg, VA | W 64-57 |
| Tue Dec 8, 9:00 ET | vs Penn State Cassell Coliseum, Blacksburg, VA | L 55-75 |
| Tue Dec 15, 6:30 ET | vs Clemson Cassell Coliseum, Blacksburg, VA | W 66-60 |
| Sat Dec 19, 5:30 ET | vs Coppin State Cassell Coliseum, Blacksburg, VA | W 97-57 |
| Mon Dec 21, 8:00 ET | vs Longwood Cassell Coliseum, Blacksburg, VA | W 84-58 |
| Tue Dec 29, 6:00 ET | vs Miami Cassell Coliseum, Blacksburg, VA | W 80-78 |
| Wed Jan 6, 6:30 ET | at Louisville KFC Yum Center, Louisville, KY | L 71-73 |
| Sun Jan 10, 6:00 ET | vs Notre Dame Cassell Coliseum, Blacksburg, VA | W 77-63 |
| Tue Jan 12, 7:00 ET | vs Duke Cassell Coliseum, Blacksburg, VA | W 74-67 |
| Sun Jan 17, 6:00 ET | at Wake Forest LJVM Coliseum, Winston-Salem, NC | W 64-60 |
| Sat Jan 23, 12:00 ET | at Syracuse The Dome, Syracuse, NY | L 60-78 |
| Wed Jan 27, 7:00 ET | at Notre Dame Purcell Pavilion Notre Dame, IN | W 62-51 |
| Sat Jan 30, 6:00 ET | vs Virginia Cassell Coliseum, Blacksburg, VA | W 65-51 |
| Wed Feb 3, 7:00 ET | at Pitt Petersen Events Center, Pittsburgh, PA | L 72-83 |
| Sat Feb 6, 12:00 ET | at Miami Watsco Center, Coral Gables, FL | W 80-76 |
| Tue Feb 23, 7:00 ET | vs Georgia Tech Cassell Coliseum, Blacksburg, VA | L 53-69 |
| Sat Feb 27, 4:00 ET | vs Wake Forest Cassell Coliseum, Blacksburg, VA | W 84-46 |
| Thu Mar 11, 8:30 ET | vs North Carolina Greensboro, NC | L 73-81 |
| Fri Mar 19, 12:15 ET | vs Florida Hinkle Fieldhouse, Indianapolis, IN | L 70-75 |