| Date | Game | |
| Mon Nov 6, 8:00 ET | vs Coppin State Blacksburg, Va. | W 100-55 |
| Fri Nov 10, 9:30 ET | vs South Carolina Charlotte, N.C. | L 77-79 |
| Wed Nov 15, 6:00 ET | vs Campbell Blacksburg, Va. | W 60-44 |
| Sun Nov 19, 5:00 ET | vs Wofford Blacksburg, Va. | W 98-76 |
| Thu Nov 23, 8:00 ET | vs Boise State Orlando, Fla. | W 82-75 |
| Fri Nov 24, 5:30 ET | vs Iowa State Orlando, Fla. | W 71-62 |
| Sun Nov 26, 1:00 ET | vs Florida Atlantic Orlando, Fla. | L 50-84 |
| Wed Nov 29, 9:15 ET | at Auburn Auburn, Ala. | L 57-74 |
| Sun Dec 3, 4:00 ET | vs Louisville Blacksburg, VA | W 75-68 |
| Sat Dec 9, 12:00 ET | vs Valparaiso Blacksburg, Va. | W 71-50 |
| Sat Dec 16, 4:00 ET | vs Vermont Blacksburg, Va. | W 73-51 |
| Thu Dec 21, 5:00 ET | vs American Blacksburg, Va. | W 77-55 |
| Sat Dec 30, 2:00 ET | at Wake Forest Winston-Salem, N.C. | L 63-86 |
| Sat Jan 6, 4:00 ET | at Florida State Tallahassee, Fla. | L 74-77 |
| Wed Jan 10, 7:00 ET | vs Clemson Blacksburg, Va. | W 87-72 |
| Sat Jan 13, 7:00 ET | vs Miami Blacksburg, Va. | L 71-75 |
| Wed Jan 17, 7:00 ET | at Virginia Charlottesville, Va. | L 57-65 |
| Sat Jan 20, 12:00 ET | at NC State Raleigh, NC | W 84-78 |
| Tue Jan 23, 9:00 ET | vs Boston College Blacksburg, VA | W 76-71 |
| Sat Jan 27, 5:00 ET | vs Georgia Tech Blacksburg, Va. | W 91-67 |
| Mon Jan 29, 7:00 ET | vs Duke Blacksburg, VA | L 67-77 |
| Sat Feb 3, 12:00 ET | at Miami Coral Gables, Fla. | L 74-82 |
| Sat Feb 10, 6:00 ET | at Notre Dame Notre Dame, Ind. | L 66-74 |
| Tue Feb 13, 9:00 ET | vs Florida State Blacksburg, Va. | W 83-75 |
| Sat Feb 17, 2:00 ET | at North Carolina Chapel Hill, NC | L 81-96 |
| Mon Feb 19, 7:00 ET | vs Virginia Blacksburg, Va. | W 75-41 |
| Sat Feb 24, 5:30 ET | at Pitt Pittsburgh, Pa. | L 64-79 |
| Tue Feb 27, 7:00 ET | at Syracuse Syracuse, N.Y. | L 71-84 |
| Sat Mar 2, 5:30 ET | vs Wake Forest Blacksburg, VA | W 87-76 |
| Tue Mar 5, 7:00 ET | at Louisville Louisville, KY | W 80-64 |
| Sat Mar 9, 2:30 ET | vs Notre Dame Blacksburg, Va. | W 82-76 |
| Wed Mar 13, 12:00 ET | vs Florida State Washington, D.C. | L 76-86 |
| Tue Mar 19, 9:00 ET | vs Richmond Blacksburg, VA | W 74-58 |
| Sat Mar 23, 7:00 ET | at Ohio State Columbus, OH | L 73-81 |