| Date | Game | |
| Thu Aug 25, 10:00 ET | at Grand Canyon Phoenix, Ariz. | L 0-1 |
| Sun Aug 28, 10:00 ET | at UCLA | Pac-12 Network |
| Fri Sep 2, 7:00 ET | vs Radford Blacksburg, Va. | T 0-0 |
| Mon Sep 5, 5:00 ET | vs Mercer Blacksburg, Va. | L 2-3 |
| Fri Sep 9, 8:00 ET | at Virginia Charlottesville, VA | L 2-4 |
| Fri Sep 16, 7:30 ET | vs Wake Forest Blacksburg, Va. | L 0-1 |
| Tue Sep 20, 7:00 ET | vs Longwood Blacksburg, Va. | W 4-0 |
| Fri Sep 23, 7:00 ET | at NC State Raleigh, N.C. | L 0-1 |
| Tue Sep 27, 7:00 ET | at Davidson Davidson, N.C. | L 1-3 |
| Fri Sep 30, 6:00 ET | vs Syracuse Blacksburg, VA | L 0-3 |
| Tue Oct 4, 7:00 ET | at ETSU Johnson City, Tenn. | W 2-0 |
| Fri Oct 7, 7:00 ET | at North Carolina Chapel Hill, N.C. | L 0-2 |
| Fri Oct 14, 5:00 ET | vs Pitt Blacksburg, VA | L 0-1 |
| Tue Oct 18, 6:00 ET | vs Princeton Blacksburg, Va. | L 0-5 |
| Fri Oct 21, 7:00 ET | at Notre Dame South Bend, Ind. | L 0-1 |
| Fri Oct 28, 6:00 ET | vs Duke Blacksburg, Va. | L 0-1 |
| Wed Nov 2, 6:00 ET | at Louisville Louisville, KY | W 2-1 |
| Sun Nov 6, 2:00 ET | at Wake Forest Winston-Salem, NC | L 0-1 |