| Date | Game | |
| Fri Sep 4 | at Old Dominion Norfolk, Va. | |
| Fri Sep 11 | vs Appalachian State Winston-Salem, N.C. | |
| Sat Sep 12, 7:30 ET | vs Clemson Winston-Salem, N.C. | L 13-37 |
| Sat Sep 19 | vs Villanova Winston-Salem, N.C. | |
| Sat Sep 19, 8:00 ET | at NC State Raleigh, N.C. | L 42-45 |
| Sat Sep 26 | vs Notre Dame Winston-Salem, N.C. | |
| Sat Sep 26 | vs Notre Dame Charlotte, N.C. | |
| Fri Oct 2 | vs Campbell Winston-Salem, NC | W 66-14 |
| Sat Oct 3, 12:00 ET | at Duke Durham, N.C. | |
| Fri Oct 9 | vs Miami Winston-Salem, N.C. | |
| Sat Oct 17 | at Florida State Tallahassee, Fla. | |
| Sat Oct 17, 4:00 ET | vs Virginia Winston-Salem, N.C. | W 40-23 |
| Sat Oct 24, 3:30 ET | vs Virginia Tech Winston-Salem, N.C. | W 23-16 |
| Sat Oct 31 | at NC State Raleigh, N.C. | |
| Sat Oct 31, 12:00 ET | at Syracuse Syracuse, N.Y. | W 38-14 |
| Sat Nov 7 | vs Syracuse Winston-Salem, N.C. | |
| Sat Nov 14 | at Louisville Louisville, Ky. | |
| Sat Nov 14, 12:00 ET | at North Carolina Chapel Hill, N.C. | L 53-59 |
| Sat Nov 21 | vs Clemson Winston-Salem, N.C. | |
| Sat Nov 28 | vs Boston College Winston-Salem, N.C. | |
| Sat Dec 12, 12:00 ET | at Louisville Louisville, Ky. | L 21-45 |
| Wed Dec 30, 12:00 ET | vs University of Wisconsin Charlotte, NC | L 28-42 |