| Date | Game | |
| Thu Sep 1, 7:30 ET | vs VMI Winston-Salem, N.C. | W 44-10 |
| Sat Sep 10, 12:00 ET | at Vanderbilt Nashville, Tenn. | W 45-25 |
| Sat Sep 17, 12:00 ET | vs Duke | RSN |
| Sat Sep 17, 5:00 ET | vs Liberty Winston-Salem, N.C. | W 37-36 |
| Sat Sep 24, 12:00 ET | vs Clemson Winston-Salem, N.C. | L 45-51 |
| Sat Oct 1, 3:30 ET | at Florida State Tallahassee, Fla. | W 31-21 |
| Sat Oct 8, 7:30 ET | vs Army Winston-Salem, N.C. | W 45-10 |
| Sat Oct 22, 3:30 ET | vs Boston College Winston-Salem, N.C. | W 43-15 |
| Sat Oct 29 | at Louisville Louisville, Ky. | L 21-48 |
| Sat Nov 5, 8:00 ET | at NC State Raleigh, N.C. | L 21-30 |
| Sat Nov 12, 7:30 ET | vs North Carolina Winston-Salem, N.C. | L 34-36 |
| Sat Nov 19, 8:00 ET | vs Syracuse Winston-Salem, N.C. | W 45-35 |
| Sat Nov 26, 3:30 ET | at Duke Durham, N.C. | L 31-34 |
| Fri Dec 23, 6:30 ET | vs Missouri Tampa, Fla. / Union Home Mortgage Gasparilla Bowl | W 27-17 |